A Red Carpet For Iron Metabolism

Department of pediatric oncology hematology and immunology im neuenheimer feld 153 69120 heidelberg germany.

A red carpet for iron metabolism.

1 molecular medicine partnership unit european molecular biology laboratory and university of heidelberg im neuenheimer feld 350 69120 heidelberg germany. Iron is essential for many of the body s metabolic functions but its main role is in the production of hemoglobin the protein within red blood cells that binds oxygen for delivery to the various organs 2. Among other themes this collection highlights a selection of seminal reviews from cell about metabolic conditions such as insulin resistance and diabetes atherosclerosis and heart disease and cholesterol biology metabolic syndrome as well as obesity and metabolic regulation of the fat tissue. Muckenthaler mu 1 rivella s 2 hentze mw 3 galy b 4.

Rolling out the red carpet. It is also one of the most abundant minerals on the planet. A red carpet for iron metabolism. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.

A red carpet for iron metabolism. Controlling iron levels in the body is a critically important part of many aspects of human health and disease. Request pdf a red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 iron atoms every second to maintain adequate. Rolling out the red carpet.

Iron is both necessary to the body and potentially toxic. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron. 2017 muckenthaler et al. Cell a red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 15 iron atoms every second to maintain adequate erythropoiesis.

Iron is one of the most important minerals in the human body. Iron metabolism in erythroid cells red blood cells rbcs are formed from lineage committed progenitors during erythropoiesis a highly regulated process. These impressive number. A red carpet for iron metabolism 200 billion red blood cells rbcs are produced every day requiring more than 2 10 sup 15 sup iron atoms every second to maintain adequate erythropoiesis.

Metabolism is the basis of any biological function from the cellular to the organismal level. Human iron metabolism is the set of chemical reactions that maintain human homeostasis of iron at the systemic and cellular level. These numbers translate into 20 ml of blood being produced each day containing 6 g of hemoglobin and 20 mg of iron.